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D/cfm.md

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---
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layout: definition
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mathjax: true
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author: "Joram Soch"
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affiliation: "BCCN Berlin"
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e_mail: "joram.soch@bccn-berlin.de"
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date: 2021-10-21 17:01
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title: "General linear model"
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chapter: "Statistical Models"
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section: "Multivariate normal data"
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topic: "Inverse general linear model"
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definition: "Corresponding forward model"
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sources:
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- authors: "Haufe S, Meinecke F, Görgen K, Dähne S, Haynes JD, Blankertz B, Bießmann F"
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year: 2014
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title: "On the interpretation of weight vectors of linear models in multivariate neuroimaging"
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in: "NeuroImage"
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pages: "vol. 87, pp. 96–110, eq. 3"
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url: "https://www.sciencedirect.com/science/article/pii/S1053811913010914"
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doi: "10.1016/j.neuroimage.2013.10.067"
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def_id: "D162"
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shortcut: "cfm"
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username: "JoramSoch"
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---
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**Definition:** Let there be observations $Y \in \mathbb{R}^{n \times v}$ and $X \in \mathbb{R}^{n \times p}$ and consider a weight matrix $W = f(Y,X) \in \mathbb{R}^{v \times p}$ estimated from $Y$ and $X$, such that right-multiplying $Y$ with the weight matrix gives an estimate or prediction of $X$:
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$$ \label{eq:bda}
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\hat{X} = Y W \; .
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$$
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Given that the columns of $\hat{X}$ are linearly independent, then
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$$ \label{eq:cfm}
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Y = \hat{X} A^\mathrm{T} + E \quad \text{with} \quad \hat{X}^\mathrm{T} E = 0
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$$
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is called the corresponding forward model relative to the weight matrix $W$.

D/iglm.md

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---
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layout: definition
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mathjax: true
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author: "Joram Soch"
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affiliation: "BCCN Berlin"
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e_mail: "joram.soch@bccn-berlin.de"
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date: 2021-10-21 15:31:00
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title: "General linear model"
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chapter: "Statistical Models"
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section: "Multivariate normal data"
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topic: "Inverse general linear model"
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definition: "Definition"
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sources:
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- authors: "Soch J, Allefeld C, Haynes JD"
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year: 2020
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title: "Inverse transformed encoding models – a solution to the problem of correlated trial-by-trial parameter estimates in fMRI decoding"
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in: "NeuroImage"
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pages: "vol. 209, art. 116449, Appendix C"
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url: "https://www.sciencedirect.com/science/article/pii/S1053811919310407"
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doi: "10.1016/j.neuroimage.2019.116449"
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def_id: "D161"
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shortcut: "iglm"
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username: "JoramSoch"
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---
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**Definition:** Let there be a [general linear models](/D/glm) of measured data $Y \in \mathbb{R}^{n \times v}$ in terms of the [design matrix](/D/glm) $X \in \mathbb{R}^{n \times p}$:
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$$ \label{eq:glm}
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Y = X B + E, \; E \sim \mathcal{MN}(0, V, \Sigma) \; .
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$$
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Then, a [linear model](/D/glm) of $X$ in terms of $Y$, under the assumption of \eqref{eq:glm}, is called an inverse general linear model.

D/tglm.md

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---
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layout: definition
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mathjax: true
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author: "Joram Soch"
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affiliation: "BCCN Berlin"
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e_mail: "joram.soch@bccn-berlin.de"
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date: 2021-10-21 14:43:00
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title: "General linear model"
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chapter: "Statistical Models"
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section: "Multivariate normal data"
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topic: "Transformed general linear model"
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definition: "Definition"
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sources:
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- authors: "Soch J, Allefeld C, Haynes JD"
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year: 2020
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title: "Inverse transformed encoding models – a solution to the problem of correlated trial-by-trial parameter estimates in fMRI decoding"
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in: "NeuroImage"
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pages: "vol. 209, art. 116449, Appendix A"
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url: "https://www.sciencedirect.com/science/article/pii/S1053811919310407"
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doi: "10.1016/j.neuroimage.2019.116449"
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def_id: "D160"
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shortcut: "tglm"
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username: "JoramSoch"
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---
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**Definition:** Let there be two [general linear models](/D/glm) of measured data $Y \in \mathbb{R}^{n \times v}$ using [design matrices](/D/glm) $X \in \mathbb{R}^{n \times p}$ and $X_t \in \mathbb{R}^{n \times t}$
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$$ \label{eq:glm1}
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Y = X B + E, \; E \sim \mathcal{MN}(0, V, \Sigma)
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$$
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$$ \label{eq:glm2}
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Y = X_t \Gamma + E_t, \; E_t \sim \mathcal{MN}(0, V, \Sigma_t)
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$$
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and assume that $X_t$ can be transformed into $X$ using a transformation matrix $T \in \mathbb{R}^{t \times p}$
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$$ \label{eq:X-Xt-T}
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X = X_t \, T
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$$
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where $p < t$ and $X$, $X_t$ and $T$ have full ranks $\mathrm{rk}(X) = p$, $\mathrm{rk}(X_t) = t$ and $\mathrm{rk}(T) = p$.
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Then, a [linear model](/D/glm) of the parameter estimates from \eqref{eq:glm2}, under the assumption of \eqref{eq:glm1}, is called a transformed general linear model.

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