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Metaproteomics Data

Rahul Mondal edited this page Jan 28, 2021 · 6 revisions

First coined in 2004, Metaproteomics deals with identifying & quantifying proteins from microbial communities to study and experiment with features and behaviour of microorganisms at a molecular level. The data, we intend to deal with from our huge Clinical Knowledge Graph, are information on peptides, proteins & metaproteins to find a connection between their abundance patients with various diseases. Hence we put forward a summary of our keywords explained briefly & the connections they share to make our queries in Neo4j more feasible to understand.

Protein

Proteins, composed of amino acids, are the most essential building block of all living organisms on the planet & are directly involved in the chemical processes, essential for life. The word itself has been derived from the Greek word "prōteios", which means "holding first place". As Encyclopaedia Britannica puts it, proteins are

  • species-specific (differs from one species to the other) as well as
  • organ-specific i.e. for e.g. within a single organism, proteins in brain will be different to proteins in liver & so forth.

Note - Proteins of similar function, have similar aminino acid composition & sequence

Peptide

Proteins & peptides are kind of similar through structural aspects. Peptides act like a subset for protein consisting between 2 - 50 amino acids held together by peptide bonds, whereas proteins consists of 50 or more mino acids

Metaprotein

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